Yad Ephraim provides a range of bikur cholim services, centered around the delivery of fresh, meals to patients and their families in hospitals and homes. The organization originally focused its efforts on Maimonides Medical Center in Boro Park, offering warm meals to patients in need. As demand increased, Yad Ephraim expanded its operations, constructing a state-of-the-art kitchen facility near the hospital to accommodate larger-scale meal production.

In addition to meal distribution, Yad Ephraim operates a 24-hour emergency hotline to ensure that patients can request assistance at any time. The organization also responds to calls for support from individuals who are homebound due to illness, extending its services beyond the hospital setting. These offerings are structured to provide both physical and emotional nourishment to those facing health challenges.

Yad Ephraim coordinates special programs around yomim tovim, delivering seasonal meals and creating uplifting experiences tailored to each yom tov. The organization also compiles and distributes a public tehillim list to encourage community tefillah for those in need of refuah. These added services reflect a broader commitment to spiritual as well as physical support for patients and their families.